The leaves and bark of the willow tree have been mentioned in ancient texts from Assyria, Sumer and Egypt as a remedy for aches and fever and the Ancient Greek physician Hippocrates wrote about its medicinal properties in the 5th century BC. Native Americans across the American continent relied on it as a staple of their medical treatments. This is because it contains salicylic acid, the precursor to aspirin.
Natural Concentrate obtained from Willow Bark.
Botanical name : Salix alba L.
Plant part used : Bark
Beige to brown powder
Studies have reported the following properties :
1) Anti-inflammatory effect
2) Anti-Arthritic effect
3) Antalgic dose-dependent
White willow bark Botanical concentrate have been used for centuries in traditionnal medicine and are believed to help for the treament of osteo-arthritis.In vitro studies with salix alba concentrate have reported anti-inflammatory and anabolic effects on chondrocytes.This activity is probably linked to other compounds than salicin and salicylates. The efficacy of willow bark concentrate in the treatment of painful mobility disorders, such as back pain and arthritis, has been attributed to the content of salicin and its derivatives as pro-drugs of salicylates.
However, based on clinical experience and the evidence of experimental pharmacological studies, the fraction of total salicin cannot satisfactorily explain the clinical efficacy of willow bark.
In addition, salicins and their metabolites lack the acetylating potential of ASA and must therefore possess a different mechanism of action. A detailed pharmacological screening of the aqueous willow bark concentrate STW 33-I addressed the question of the identification of fractions contributing to the overall effect.
All in vivo and in vitro models studied pointed to relevant contributions of the fraction of polyphenols and flavonoids. The single compounds or their combinations responsible for the effect remain to be elucidated.